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Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression

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An experiment revealed that polyphyllin VI (PPVI), a bioactive ingredient extracted from the traditional Chinese medicine Paris polyphylla , increases ROS accumulation, which in turn activates ROS-regulated JNK and p38 pathways and regulates the G2/M phase to inhibit glioma cell proliferation (Liu et al., 2020)

The dark proteome of cancer: Intrinsic disorderedness and functionality of HIF-1 along with its interacting proteins, in Progress in Molecular Biology and Translational Science , Elsevier, 2019, pp