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Fatigue, weakness, dizziness, numbness, tingling, poor balance, irritability, depressed mood, forgetfulness, constipation or diarrhea, sore tongue or mouth sores, shortness of breath, and poor growth and development in children may indicate a higher need for vitamin B12 intake

Developed primarily for preclinical research targeting metabolic dysfunction, it elevates intracellular NAD+ pools via NNMT suppression to regulate lipid metabolism, insulin sensitivity and overall bodily metabolic function

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For those with a B12 deficiency, initial injections may be given more frequently, such as weekly or bi-weekly, until levels are restored

People with kidney conditions should be cautious with high-dose B12