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In contrast to His-IMAC chelate binding, GST-tagged proteins bind noncovalently to an affinity matrix composed of glutathione immobilized on a chromatographic support

Unlike trigeminal neuralgia, which involves short (seconds to minutes) episodic, sharp, electric-like pain affecting one or more branches of the trigeminal nerve, CTN often manifests as continuous pain or sensory disturbances [1]

Similar to calcitriol, Klotho is involved in the calcium and phosphate homeostasis (Kim et al

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