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1997), further sensitizing cells to Fas-mediated apoptosis

Those with a longer duration of NSAID treatment, who are concomitantly using oral corticosteroids, aspirin, anticoagulants, selective serotonin reuptake inhibitors (SSRIs), or serotonin and norepinephrine reuptake inhibitors (SNRIs), and who have a history of liver disease, peptic ulcers, GI bleeding, or bleeding disorders are at an increased risk

Approximately 12 percent of the Caucasian population is homozygous for thermolabile MTHFR

J Appl Physiol 58:571574 Ellinger-Ziegelbauer H, Gmuender H, Bandenburg A, Ahr HJ (2008) Prediction of a carcinogenic potential of rat hepatocarcinogens using toxicogenomics analysis of short-term in vivo studies