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Some studies show a 30% reduction in certain cancers with supplementation, though results remain mixed

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In a second work (127), the authors investigated the role of crocetin, a component of saffron stigma, which has significant therapeutic effects on various diseases, including cancers

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The multiplex kit was used to quantify the secretions of CRP, Eotaxin, Eotaxin-3, FGF(basic), Flt-1, GM-CSF, ICAM-1, IFN-, IL-10, IL-12/IL-23p40, IL-12p70, IL-13, IL-15, IL-16, IL-17A, IL-17A/F, IL-17B, IL-17C, IL-17D, IL-1RA, IL-1, IL-1, IL-2, IL-21, IL-22, IL-23, IL-27, IL-3, IL-31, IL-4, IL-5, IL-6, IL-7, IL-8, IL-8 (HA), IL-9, IP-10, MCP-1, MCP-4, MDC, MIP-1, MIP-1, MIP-3, PlGF, SAA, TARC, Tie-2, TNF-, TNF-, TSLP, VCAM-1, VEGF-A, VEGF-C and VEGF-D