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found that knockdown of low-density lipoprotein receptor-related protein 1 (LRP1) enhances cellular glucose uptake and glycolytic capability by increasing the density of glucose transporter type 1 (GLUT1) on the astrocyte membrane

When FXR binds to its ligand, it gets activated and reaches the cell nucleus, where it forms a heterodimer with RXR

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Mitochondrial stress stimulates the cleavage of DELE1 by the protease OMA1, resulting in the accumulation of the C-terminal domain of DELE1 in the cytosol

Liu W, Baker SS, Baker RD, Zhu L