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Conclusion: This innovative care model can reach WHO HCV elimination goals by improving access and linkage to care, improving time to treatment, and increasing HCV cure rates

FSEN1 was identified as a small-molecule inhibitor of FSP1 through chemical screening 118 , and subsequent structural analyses revealed that FSEN1 occupies the substrate-binding pocket of FSP1 in a position analogous to CoQ observed in the enzyme active site, providing structural insight into inhibitor recognition 119

The vCD44BP virus replicated in permissive cell types with kinetics that were indistinguishable from those of the parent virus (Extended Data Fig

Consistent with the expression of HGF and c-MET mRNA, ZH-161 and ZH-305 exhibited basal levels of phosphorylated c-MET (p-c-MET) as demonstrated by immunoblot and immunocytochemistry (Fig