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The MHRA advises checking B12 levels in patients taking metformin who develop symptoms of deficiency or have risk factors, with periodic monitoring in at-risk patients

Mericq V, Romn R, Iiguez G, Angel B, Salazar T, Avila A, Perez-Bravo F, Cassorla F

Flash column chromatography was performed on Biotage Isolera One 2.2 using commercial columns that were pre-packed with Merck Kieselgel 60 (230-400 mesh) silica gel