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Int J Mol Sci 25(16):8792 Chimento A, DAmico M, De Luca A, Conforti FL, Pezzi V, De Amicis F (2023) Resveratrol, epigallocatechin gallate and curcumin for cancer therapy: Challenges from their pro-apoptotic properties

The mechanisms involve reducing oxidative stress and inflammation by modulating ROS, AP-1, MMP-1/3, IL-1, SOD, CAT, GSH-Px, TGF-1, Smad2/3, and increasing pro-collagen I expression [25]