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Si bien normalmente son el resultado del estrs, los radicales libres pueden ser causados por otros factores ambientales como el humo y los contaminantes

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The following siRNA duplex was used for silencing Tfeb expression: siRNA sense: 5 GGAUCAAGGAGCUGGGAAUUU 3, antisense: 5 AUUCCCAGCUCCUUGAUCCUU 3 (Dharmacon)