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However, no large-scale human clinical trials have been completed, so long-term safety data in humans remains limited

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Theres a big gap from GLP-1s to the others on the list above , which includes 2 growth-hormone releasing hormone peptides

What makes them noteworthy is the novelty of their targets: Dihexa works through the hepatocyte growth factor (HGF) / c-Met receptor system, while PE-22-28 blocks TREK-1 two-pore domain potassium channels