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Notably, TrxR1 exhibits elevated levels of expression across a spectrum of malignancies, encompassing hematological neoplasms such as lymphoma and multiple myeloma, underscoring its potential as a therapeutic target in oncology (185)

Supporting this hypothesis, we observed that despite the more oxidised than expected cytosolic NADP redox state, it seems to be coupled with a remarkable robustness to perturbation by exogenous oxidants in both yeast and mammalian cells

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Glutathione plays an important role in good skin health and can improve the brightness of the skin

But supplementing with NAC may help keep those levels topped up