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[7] It is essential not to read a pending submission as an approval: a filing under review is not a marketing authorization, and cagrilintide may not be prescribed, dispensed, or sold for human use

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Thus, microbial changes in PD indicate a shift from a symbiotic, neuroprotective microbiota to a pro-inflammatory, neurotoxic microbial composition, which can promote peripheral immune activation, gut barrier failure, and, eventually, neuroinflammation and dopaminergic neuronal death [44]

If the cap or stopper looks compromised, do not use it