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Meller J, Vidali L, Schwartz MA (2008) Endogenous RhoG is dispensable for integrin-mediated cell spreading but contributes to Rac-independent migration

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The upregulation of ser/gly synthesis enzymes has been observed in aggressive radiotherapy treated cancers and was described to increase even further under hypoxia, to produce antioxidants to neutralize reactive oxygen species (ROS) and relieve cellular oxidative stress, thereby promoting the survival of radiotherapy treated cancer cells [6,7,8,9,10,11]

Muncke J, Andersson AM, Backhaus T, Boucher JM, Carney Almroth B, Castillo Castillo A, Chevrier J, Demeneix BA, Emmanuel JA, Fini JB, Gee D, Geueke B, Groh K, Heindel JJ, Houlihan J, Kassotis CD, Kwiatkowski CF, Lefferts LY, Maffini MV,

Neutrophil cytosolic factor 1 (NCF1) is a significant genetic factor linked to autoimmune disorders, and NOX2-derived ROS are observed specifically in the mutated NCF1 gene, contributing to the malfunctioning of NCF1 in lupus