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The substrates of this alteration are directed to the polyol pathway, which, at normal glucose concentrations, is not active [38]

In exploring the bio-applicability of HGII -type catalysts, previous work has mainly focused on cytotoxicity and the presence of potentially inhibiting biomolecules, such as those containing thiol groups [16, 28]

doi: 10.1016/j.cell.2020.07.038

When the functional group attacking the peptide bond is a thiol, hydroxyl or amine, the resulting molecule may be called a cyclol or, more specifically, a thiacyclol, an oxacyclol or an azacyclol, respectively

Huang-Lian-Jie-du decoction drug-containing serum inhibits IL-1 secretion from D-glucose and PA induced BV2 cells via autophagy/NLRP3 signaling