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Plasma trimethylamine N-oxide and its precursors: population epidemiology, parentchild concordance, and associations with reported dietary intake in 11-to 12-year-old children and their parents

TGF-1 contributes to disease progression by promoting fibroblast proliferation, thickening of synovial tissue, and the breakdown of cartilage through enzymes such as aggrecanase-1

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The trimeric complex translocates to the nucleus and regulates different target gene expressions in concert with transcriptional co-activators and co-repressors