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Sunlight, pollution, and stress create unstable molecules called free radicals that bump into healthy structures and cause damage over time

doi: 10.1021/bi951930b

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Zinc deficiency exacerbates these processes by upregulating molecules like vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1), facilitating monocyte attachment and intensifying vascular inflammation and AS progression [475, 476]