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Ozempic is FDA-approved to treat Type 2 diabetes, and Wegovy is FDA-approved for weight loss

Increases circulating IGF-1 levels: Endogenous GH released in response to tesamorelin upregulates hepatic IGF-1 production, leading to enhanced lipolytic, anabolic, and metabolic activity throughout peripheral tissues 1

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In fact, some evidence suggests that long-term calorie restriction may even increase it a bit