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It indicated that daily oral delivery of LRE substantially preserved retinal ganglion cell function and survival

36,37 Zonula occludens (ZO), including ZO-1 and its homologs ZO-2 and ZO-3, is a group of PDZ-related scaffolding proteins that belong to the superfamily of membrane-associated guanylate kinase-like proteins, possessing sites of three tandem PDZ domains at the N-terminus 38,39 (Figure 1)

Proteomics 19 (18), e1800311

These bigwigs, along with the previously obtained induced and reduced peaks in bed format, were input into deeptools computeMatrix, and the output was plotted using deeptools plotHeatmap reference-point

Brain punches were obtained using a cryostat, and RNA was extracted using the Promega RNA extraction kit