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1888 The first observation Joseph de Rey-Pailhade, University of Montpellier, working with yeast extract The substance was first described in 1888 by Rey-Pailhade, who named it philothion and recorded its ability to reduce elemental sulphur

Biol Trace Elem Res 187(1):316327 Kieliszek M, Lipinski B (2018) Pathophysiological significance of protein hydrophobic interactions: An emerging hypothesis

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If burping persists beyond 12 weeks despite dose stabilization, underlying digestive conditions or medication interactions may be involved

You S, Ma Z, Zhang P, Xu W, Zhan C, Sang N, et al