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The antidepressant properties of Pure Essence, documented in the prescription compendium of the Taiping Welfare Pharmacy Bureau during the Song Dynasty, have been thoroughly validated through TCM theory, clinical applications, and pharmacological research

It is found in every cell of the body and serves as the first line of defense, with particularly high levels in the liver, kidneys, lungs, adrenal glands, reproductive organs, brain and pancreas

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GPx4 knockdown significantly enhanced CSE-induced lipid peroxidation in HBECs (Fig