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The sixth coordination site, the reactive center, is variable, being a cyano group (CN), a hydroxyl group (OH), a methyl group (CH 3 ) or a 5-deoxyadenosyl group

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Histamine Intolerance & DAO Enzyme Deficiency Some individuals with MCAS also have histamine intolerance, meaning their body struggles to break down histamine due to a deficiency in diamine oxidase (DAO), the enzyme responsible for histamine degradation

Available data indicating BPC 157 can facilitate muscle and tendon healing are limited to rat and in vitro studies, with one small, low-quality observational study in humans determining BPC 157 can help improve knee pain (see Table 1)