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Overactivation of STAT3 skews the immune balance by promoting T helper 17 (Th17) cell expansion while suppressing Treg function

Other Articles Zhang, S, Jiang, VC, Han, G, Hao, D, Lian, J, Liu, Y, Cai, Q, Zhang, RJ, McIntosh, J, Wang, R, Dang, M, Dai, E, Wang, Y, Santos, DA, Badillo, M, Leeming, A, Chen, Z, Hartig, K, Bigcal, J, Zhou, J, Kanagal-Shamanna, R, Ok, CY, Lee, H, Steiner, RE, Zhang, J, Song, X, Nair, R, Ahmed, S, Rodriquez, A, Thirumurthi, S, Jain, P, Wagner-Bartak, N, Hill, H, Nomie, K, Flowers, CR, Futreal, A, Wang, L, Wang, L Longitudinal single-cell profiling reveals molecular heterogeneity and tumor-immune evolution in refractory mantle cell lymphoma

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To meet the metabolic demand of immune cells, systemic metabolic remodeling is required

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