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Titulaer JM, Wirtz PW, Wintzen AR, et al

The investigators reported partial restoration of the circadian melatonin rhythm in elderly subjects following the epithalamin course, with measurable but incomplete return toward younger-adult patterns of nocturnal melatonin secretion [2]

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"There's just not enough clinical data to say whether these peptides are safe and effective," said Alexander Weber, an orthopedic surgeon and chief of sports medicine at the University of Southern California