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According to another aspect, the yeast is a mutant strain of Saccharomyces cerevisiae which has at least a mutation in a gene affecting endoplasmic reticulum function, the Golgi to endosome to vacuole transportation pathway, or vacuolar function wherein said gene is selected from: YFL031W (HAC1), YDR027C (LUV1IVPS54)

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They are often studied for their role in cell communication, immune response regulation and as cargo carriers for potential treatments