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Probing for consanguinity may be helpful especially when an autosomal recessive disorder is being considered in the differential diagnosis

Creatine is actively transported, and its absorption, distribution and clearance depend on the doses supplemented and the integrity of its transporter (SLC6A8) [23]

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The mRNA expression of myelin protein genes, such as proteolipid protein (PLP), myelin-associated glycoprotein (MAG), and myelin basic protein (MBP) is dramatically down-regulated already at week 1 (Morell et al., 1998