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They are fundamentally different systems

The good news is that patients can continue to recover indefinitely

Mechanistic studies identify a tripartite metabolic axisgluconeogenesis, glycogen metabolism, and the pentose phosphate pathway (PPP)as essential for memory T cell survival

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The rest of the mice receive 5-FC (500 mg/kg/dose, IP, BID) for 4 consecutive days, plus Lomustine at day 1 (Lomustine (CCNU) Day 1 + 5-FC) or day 43 (Lomustine (CCNU) Day 43 + 5-FC)