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Additionally, it increased Smad7 mRNA expression to inhibit UV-induced collagen degradation, confirming that PCs enhance skin conditions via activation of the TGF- /Smad signaling pathway, thus indicating its potential for delaying skin aging

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Human embryonic kidney cells HEK293T, normal lung epithelial cells (16HBE, HBEC), and NSCLC cells (A549, PC9) were obtained from the American Type Culture Collection (ATCC