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Concurrently, mtROS stimulates lipid peroxidation, ultimately leading to disruption of mitochondrial membrane potential and mitochondrial calcium buffering capacity (36)

Cell viability, glucose-stimulated insulin secretion, cellular adenosine triphosphate, reactive oxygen species (ROS) levels and Rho kinase (ROCK) activities were measured

Due to inappropriate assessment models, inadequate understanding of nanobio-interactions, etc., current macrophage nanomedicines rarely achieve practical clinical translation [311], as evidenced by their limited commercialization

The adiabatic ionization potential (AIP), the adiabatic electron affinity (EAad) and all energies (not including the zero-point energies) in H2O solvent given in this paper were calculated by performing B3LYP/6-311++G (d, p) single-point energy calculations at the optimized geometries from the B3LYP/6-31+G (d, p) calculations in gas-phase using the polarized continuum model (PCM) (Miertus et al., 1981