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PhD thesis

Despite their ability to cross the BBB, exosome therapeutics face challenges related to off-target accumulation in non-brain organs, such as the liver and spleen

Of note, consistent with post-translational mTOR inhibition by rapamycin, MYC was significantly upregulated, yet MYC targets were significantly downregulated (Fig

Development and validation of humanized mice models implanted with patient derived colorectal cancer xenografts 17(13S), 2017

In contrast, ARG2 is expressed in mitochondria of multiple tissues, with the most abundant expression in the kidney and prostate, and mediates arginine/ornithine balance