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Other common side effects include diarrhea, constipation, abdominal pain, vomiting, and decreased appetite

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Disclosures: Naoya Tsumura: Nothing to Disclose, Kazuo Imagawa: Nothing to Disclose, Ken Kato: Nothing to Disclose, Osamu Ohara: Nothing to Disclose, Ryuta Nishikomori: Nothing to Disclose, Tatsuki Mizuochi: Nothing to Disclose 2484 DEEP PHENOTYPING OF A NORTH AMERICAN COHORT OF BILE ACID SYNTHETIC DISORDERS Alyssa Kriegermeier 1 Krupa Mysore 2 Estella Alonso 1 Aki Asai 3 Kevin Bove 3 Laura Bull 4 Nathan Goodrich 5 Steve Guthery 6 Sanjiv Harpavat 7 Simon Horslen 8 Evelyn Hsu 9 Karen Jones 10 Binita Kamath 11 Saul Karpen 12 John Magee 13 Jean Molleston 14 Alexander Miethke 15 Philip Rosenthal 4 Ronald Sokol 16 Kenneth Setchell 3 Benjamin Shneider 17 Richard Thompson 18 Pamela Valentino 19 Wen Ye 10 Kathleen Loomes 20 Rohit Kohli 21 , 1 Ann and Robert H

They reported 100 cases of terminal cancer, independently assessed and refractory to conventional treatment, who lived on average four times longer than 1000 age- and disease-matched controls