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10.1016/S0891-5849(99)00247-6 Free Radic

Upon activation, phosphorylated Nrf2 translocates to the nucleus, where it binds to AREs and promotes the expression of antioxidant proteins, including HO-1 and NQO1 (64, 65)

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A study published in the Journal of the American Academy of Dermatology found that Diane 35 was significantly more effective than placebo in reducing acne lesions and improving overall skin appearance