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In a 2001 paper entitled Steps Following Attainment of Remission: Discontinuation of Antidepressant Therapy, Richard C Shelton MD observed: He gives the following recommended taper rates: *It should be noted that the advice that tapering is not needed for Fluoxetine due to its long half-life is commonly given but has been challenged in a Lancet paper by David Taylor and Mark Horowitz

The full effect develops over four to six months as you reach maintenance doses and establish consistent patterns

The listing states purity at or above 99 percent by LC MS and provides the 5 mg and 10 mg lyophilized vial options so laboratories can align ordering to project scale and batching logic