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In contrast, one would have predicted significantly increased serum levels of lactate and carboxylic acid markers of hypoxia (e.g., succinate) in patients with COVID-19, similar to that seen in patients following ischemic (71) or hemorrhagic shock (72)

We critically analyze ongoing controversies in the field, including the debate over glycolytic versus OXPHOS dependency in NSCLC subsets, and discuss emerging therapeutic vulnerabilities such as ferroptosis