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Pharmacological Inhibition of the Voltage-Gated Sodium Channel Nav1.7 Alleviates Chronic Visceral Pain in a Rodent Model of Irritable Bowel Syndrome

"Peptide therapy for male infertility: A systematic review and meta-analysis." Human Reproduction, 2024;39(1):123-134

Insulin sensitivity effects described in some preclinical studies

These include: Coronary artery disease Arrhythmias Heart defects occurring from birth Narrowed or blocked blood vessels that may lead to a heart attack or stroke Cardiomyopathy or weak heart muscles All of these conditions and others can lead to damage to heart muscle cells which can then affect the functioning of your heart

DNA is particularly vulnerable, as oxidative lesions such as eight-oxoguanine accumulate, leading to replication errors and genomic instability