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Nat Commun (2020) 11(1):2687

Vilela et al., 2020), and boosting the expression of neurogenesis-related and proliferative genes in aged animals (He et al., 2017) and enhanced aquaporin 4 expression and localization to astrocytic end feet

Furthermore, the lag period before telomere shortening occurs following TERT inhibition is problematic for aggressively proliferating tumors such as GBMs (4,6,7)