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Br.J Pharmacol 134: 737744, 2001

consequently, extrahepatic manifestations related to this mutation (diarrhoea, fever) are scarce compared to those related to ATP8B1 [55]

Photo of some ORO cowboys by the famous cowboy photographer, Jay Dusard.

Although the mechanism is not clear, research in animals suggests that riboflavin deficiency may impair iron absorption, increase intestinal loss of iron, and/or impair iron utilization for the synthesis of hemoglobin (16)