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The hyper-concentrated mix in Scenario 3 might be suitable for protocols requiring very large doses, but it introduces a higher margin for error with smaller dose measurements

Related Ang IV analogues were studied as well, such as Nle-Ang IV 2 (Nle-Tyr-Ile-His-Pro-Phe) and the endogenous LVV-hemorphin-7 3 (Leu-Val-Val-Tyr-Pro-Trp-Thr-Gln-Arg-Phe), both with structural similarities to Ang IV at the N-terminal part of the peptides (Figure 1)

Reshaping human antibodies for therapy Nature 1988 332 : 323327 Graham FL et al

and the Fundamental Research Funds for the Central Universities of Central South University (grant numbers: CX20210344)

1H-1H TOCSY spectrum of 1-propanol in D2O