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The loss of insulin sensitivity of hippocampal CA1 pyramidal neurons can subsequently cause long-term Ca 2+ -dependent afterhyperpolarizations (AHPs), which can produce significant cognitive and memory impairment in the short term and throughout life, contributing to depression (122, 123)

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igf 1 lr3 minimize side effects Application and benefits of IGF-1 LR3_Chemicalbook Igf 1 Lr3 How to

10.1016/j.jclepro.2018.05.028 146

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