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Signs and symptoms of autism include: Speech delay or regression Delay in normal childhood milestones, such as walking Sensitivity to sound or to certain noises No reciprocal gestures, such as responding to games A child 6 months of age or older that does not smile or has stopped smiling Repetitive behaviors are common Often times the child doesnt want to be touched Loud noises can be extremely disturbing to the child In addition to these symptoms, systemic inflammation, gastrointestinal immune-related problems, and changes in the gut microbiota are characteristic for people with autism (1)

Protein A ELISA Titrated amounts of NIP IgG1 WT or REW (1000.00.78 ng/mL) was captured on BSA-NIP(25) (diluted to 1 g/mL in PBS) coated in 96-well EIA/RIA plates (CorningCostar) pre-blocked with PBS/S

The ZIP6/ZIP10 heteromer is also critical for triggering zinc-mediated mitosis, 156 forming a zinc-dependent mitotic complex consisting of ZIP6, ZIP10, pS 727 STAT3, and pS 38 Stathmin, which play roles in proven mitotic pathways

Complement activation, cytotoxicity, and alterations in cell junction proteins (e.g., reduced connexin-43) may also exacerbate tissue injury(Wroska et al., 2024)