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l-Ergothioneine modulates oxidative damage in the kidney and liver of rats in vivo : studies upon the profile of polyunsaturated fatty acids

This review first outlines the pathways of MPs exposure through the skin and intestinal absorption, emphasizing that nanoplastics can penetrate the stratum corneum or enter the body via endocytosis and paracellular routes in the intestinal epithelium, damaging both skin and intestinal epithelial barriers, inducing oxidative stress, and causing immune imbalance

NRF2 then transcriptionally activates ATG genes, helping to mitigate ROS and maintain homeostasis (60-62)

Biomed Pharmacother 162:114606 Jomova K, Alomar SY, Alwasel SH, Nepovimova E, Kuca K, Valko M (2024) Several lines of antioxidant defense against oxidative stress: antioxidant enzymes, nanomaterials with multiple enzyme-mimicking activities, and low-molecular-weight antioxidants

Do not use if you are pregnant or breastfeeding, or have cystinuria