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4.7 Effect on neonatal respiratory distress syndrome Premature infants diagnosed with neonatal respiratory distress syndrome (RDS) exhibit significantly diminished plasma levels of L-carnitine compared to their non-RDS counterparts (69)

Collectively, the synergistic action of AGE-RAGE signaling, metabolic rewiring, and oxidative stress in the DW microenvironment creates a powerful, self-reinforcing circuit that locks macrophages into a persistent M1 state, thereby perpetuating chronic inflammation and impeding the resolution of healing (Figure 3)

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The American Association for Respiratory Care recommends humidification for all mechanically ventilated patients

Rastegar-Pouyani N, Montazeri V, Marandi N, Aliebrahimi S, Andalib M, Jafarzadeh E, Montazeri H, Ostad SN (2023) The impact of cancer-associated fibroblasts on drug resistance, stemness, and epithelial-mesenchymal transition in bladder cancer: a comparison between recurrent and non-recurrent patient-derived CAFs