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Common sleep-related symptoms include: Difficulty falling asleep, despite feeling physically tired Frequent nighttime awakenings, often with heightened alertness Restless or fragmented sleep, leading to non-restorative rest Vivid, intense, or emotionally charged dreams, sometimes remembered in detail Night sweats, particularly during early withdrawal Feeling wired at night but exhausted during the day, reflecting circadian disruption The brain gradually restores natural sleep regulation

This testing may be required to assess the performance of the device in a tropical climate or to assess the safety of the device for use by the Singapore population

Early data suggests it does

Patients unsuitable for HSCT and those with a very prolonged CR can be managed with repeated cycles of ATO (e.g

However, the conservative approach is waiting until skeletal maturity and the early 20s when growth plates are fully closed and endocrine systems are mature