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Intestinal diseases In studies on MSCs therapy for colitis, multiple lines of evidence have demonstrated that MSCs can exert antioxidant, anti-inflammatory, and mucosal repair effects through activation of the Nrf2 pathway

The high frequency in the meningococcal population of allelic variants coding for proteins with reduced functionality involved in DNA mismatch repair encoding proteins (MutS, MutL) and homologous recombination (RecB, RecC, UvrD) (Feil et al., 1999

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Their use constitutes off-label administration, and the current clinical evidence for their efficacy in this context is limited

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