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Switching from Dispersible to Film Coated Tablet Formulation of Deferasirox Improves Hemoglobin Levels and Transfusional Interval in Patients with Transfusiondependentthalassemia

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Interestingly, interventions that boost NAD + levels resulted in extended lifespan in worms and mice 108,109,111,247 , suggesting a therapeutic potential for raising NAD + in various pathological conditions or age-associated diseases

3.3.2 Nrf2 activators The activation of Nrf2-ARE signaling pathway also plays an important role in protecting against mitochondrial dysfunction through promoting mitophagy (Ran et al., 2022)