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Adverse outcomes among patients on MTX include hepatotoxicity, hematotoxicity, testiculopathy, and lung problems (Shea et al., 2013)

Curr Med Res Opin 35(10):18251835

Lee KY, Kim SJ, Cha YS, So JR, Park JS, Kang KS, et al

Most patients with BPI struggle to do basic everyday tasks, like showering, dressing, and eating

If you notice that youre experiencing unusual or worsening cramps, take a break from the cold therapy next month, and then feel free to resume once your period is complete