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Indian heart journal , 76 Suppl 1 (Suppl 1), S121S129

However, the canonical ligand for TLR-4 is LPS, which is commonly found on cell walls of gram-negative bacteria (180) In LPS-driven models, LPS is either systemically administered or focally injected into the SN (181)

Nuclear translocation and transcription of antioxidant genes Upon dissociation, NRF2 translocates into the nucleus, where it binds to antioxidant response elements (AREs) located in the promoter regions of its target genes, thereby initiating their transcription

While collagen can be obtained from the diet, a more measurable way of increasing your intake is to take it in supplement form