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When histopathologic features were studied, 6% to 8% of primary melanomas were found to be in contiguity with nevi that had microscopic features characteristic of CNN.14,15 These findings support the concept of melanoma risk even with small congenital nevi, given the expected chance association based on body surface area considerations.16 For cranial, midline, or CNN with multiple satellite lesions, there is a risk of leptomeningeal involvement

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Cavalcanti F, Gonzalez-Rey E, Delgado M, Falo CP, Mestre L, Guaza C, et al

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