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2b, Supplementary Methods)

At the age of just 16, I was oddly drawn to its high-tech aesthetic and the marketed promise of sculpted cheekbones (a facial feature I considered aspirationally mature at the time)

Less Emotional Eating As hunger hormones like ghrelin decrease and mood regulation improves with B12 support, patients often report a drop in emotional eating

In contrast, treatment with natural compounds would counteract these effects by inducing the Nrf2/KEAP1 signaling pathway and reinforcing antioxidant defenses

Calculation of Testicular Index The testicular index was calculated using the following formula: Testis weight (g)/Body weight (g) 100% [26]