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Pilot studies of low-intensity vibration show that it may reduce symptoms and improve physical function in cancer survivors, but larger trials are needed to confirm these benefits (Krasnow et al., 2025

Importantly, BDNF and potentially also the other neurotrophins can be released from many non-neuronal cell types using similar molecular mechanisms

Further, a decline in inflammatory markers IL-6, TGF-1, and TNF- was also observed

Endotoxin testing is particularly critical because lipopolysaccharides, the endotoxins produced by gram-negative bacteria, are potent inflammatory triggers

More importantly, this nano-preparation retained the therapeutic effect of Melittin on melanoma models and pre-cancerous skin damage